Prevalence of Elevated Hepatic Enzymes among North Indian Patients with Type 2 Diabetes Mellitus

This study was planned to evaluate the liver function in patients with type 2 diabetes mellitus by measuring bilirubin (total and direct), aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma glutamyl transpeptidase (GGT), total protein, albumin and glycosylated hemoglobin (HBA1c) .The study was carried out in Santosh Medical College & Hospital, Ghaziabad. 100 patients with type 2 diabetes mellitus (49 males and 51 females) were included in the study. Their ages ranged between 32 and 55 years. Hundred matched normal individuals were taken as control group. In the present study, we concluded that the mean values of ALT, AST and GGT were significantly higher in patients as compared to the controls (P<0.05). Total protein and albumin concentrations in patients were lower as compared to the control group (P<0.05). The mean of serum glucose and glycosylated hemoglobin concentrations in patients revealed significant difference (P<0.001) as compared to the control group.